Karen Read pleaded not guilty to murder charges in the death of Boston police officer John O’Keefe and is facing a retrial after a jury was unable to reach a verdict last year.

After nine months of anticipation, Read’s second murder trial in the death of Boston police officer John O’Keefe began Tuesday with opening statements and the testimony of a paramedic and one of Read's friends.

Karen Read's second murder trial began Tuesday with new faces at the prosecutor's table but the same central defense claim as her first trial: she didn't kill her Boston police officer boyfriend in 2022.

Karen Read’s second murder trial began Tuesday with a prosecutor saying the defendant’s own words will bolster evidence that she killed her police officer boyfriend three years ago and a defense attorney calling the case “the definition of reasonable doubt.

The prosecution alleges that Karen Read struck her boyfriend, John O'Keefe, with her SUV then left the scene as the area was hit with a major blizzard.