The peripheral and central components in sustained clonus were investigated. The excitability of the motoneurons responding to maintained stretch by clonus was examined by tendon taps, trains of ...

1 Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, University of Toronto, Ontario, Canada 2 The Edmond J Safra Program in Parkinson's Research, Toronto Western Hospital, ...

Background and objective: Non-infectious causes of fever are often considered in critical neurological patients but their true significance has not been formally studied. The aim of this study was to ...

Dr George Woodward, Neurology Section (111), VA Medical Centre, Leavenworth, Kansas 66048, USA. Telephone 001 913 682 2000 extension 2441; fax 001 913 758 4225. If you wish to reuse any or all of this ...

Objectives: Bilateral chronic high frequency stimulation of the subthalamic nucleus (STN), through the stereotactical placement of stimulating electrodes, effectively improves the motor symptoms of ...

Anxiety is an adaptive response that promotes harm avoidance, but at the same time excessive anxiety constitutes the most common psychiatric complaint. Moreover, current treatments for anxiety—both ...

Objectives To use a data-driven approach to determine the existence and natural history of subtypes of Parkinson’s disease (PD) using two large independent cohorts of patients newly diagnosed with ...

Correspondence to Dr Karen L Furie, Neurology, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA; KFurie{at}lifespan.org ‘Post hoc’ is Latin for ‘after this’. Post hoc ...

Background We aimed to investigate the clinical, imaging and fluid biomarker characteristics in patients with antidiacylglycerol lipase alpha (DAGLA)-autoantibody-associated cerebellitis. Methods ...

Background Alzheimer’s disease (AD)-related neuropathological changes can occur decades before clinical symptoms. We aimed to investigate whether neurodevelopment and/or neurodegeneration affects the ...

4 Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau - Universitat Autònoma de Barcelona, Barcelona, Spain 5 Université de Strasbourg, Hôpitaux ...

Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...